The enterprise leadership major presents a unique blend of skills, theory, and content, encouraging students to apply their knowledge and skills to entrepreneurial concepts and ventures. The program offers a combination of business and liberal arts approaches and allows students to hone their skills in critical thinking and communications. 

The major in enterprise leadership is offered jointly by the College of Liberal Arts and Sciences and the John Pappajohn Center for Entrepreneurial Management in the Tippie College of Business. The program is administered by the John Pappajohn Entrepreneurial Management Center and the degree is awarded by the College of Liberal Arts and Sciences.

Students may earn the major in enterprise leadership or the certificate in entrepreneurial management, but not both.