Medical diagnostics is a clinical-oriented science program that incorporates the basic science courses required for admission to medical school with medical-related courses that impact on the diagnosis and therapy of disease. This major prepares students who plan to pursue postgraduate study in health-related areas immediately upon graduation, including careers in medicine, dentistry, optometry, and physician assistant.

Students with the goal of attending Medical School should visit UD's Pre-Med website for advising and admission information. There are two distinct pathways by which students can gain admission to a professional school. One is open to all majors and requires a basic knowledge of science and mathematics. Students taking this option are evaluated by the Health Science Advisement and Evaluation Committee (HSAEC), which writes a University of Delaware recommendation to medical institutions of the student's choice.

Freshmen enter as medical laboratory and diagnostics interest majors. In order to enter the medical diagnostics major at the end of the sophomore year certain criteria are required: a minimum 3.00 GPA for the first four semesters, including successful completion of prerequisite courses in chemistry, biological sciences, physics and/or anatomy and physiology, and completion of at least 60 credit hours, including the prerequisite courses. Admission to the junior/senior major is determined by academic achievement.